What is Osphena?

Osphena (ospemifene) is a treatment for moderate to severe painful intercourse, a symptom of changes in and around the vagina, due to menopause.

A NON-ESTROGEN
OPTION...

Osphena is the only FDA-approved, NON-ESTROGEN, ORAL pill that actually improves certain vaginal tissue and significantly relieves moderate to severe painful intercourse due to menopause.

Just one pill a day
with food.

Learn more about treatment with Osphena,
how it works, and what to expect.

Learn more Not actual size.

SEXafter
menopause shouldn’t have to hurt.

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Important Safety Information

Most Important Information you should know about Osphena

Osphena (ospemifene) works like estrogen in the lining of the uterus, but can work differently in other parts of the body.

Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus, strokes, and blood clots. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell them right away if this happens while you are using Osphena.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you get changes in vision or speech, sudden new severe headaches, and severe pains in your chest or legs with or without shortness of breath, weakness and fatigue. Osphena should not be used if you have unusual vaginal bleeding; have or have had certain types of cancers (including cancer of the breast or uterus); have or had blood clots; had a stroke or heart attack; have severe liver problems; or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

Possible side effects

Serious but less common side effects can include stroke, blood clots, and cancer of the lining of the uterus.

Common side effects can include hot flashes, vaginal discharge, muscle spasms and increased sweating.

Tell your healthcare provider about all of the medicines you take as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

Please read the Patient Information for OsphenaTM (ospemifene) tablets, including Boxed WARNING in the Full Prescribing Information.

Most important information

you should know
about Osphena

Osphena works like estrogen in the lining of the uterus, but can work differently in other parts of the body.

Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus, strokes, and blood clots. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell them right away if this happens while you are using Osphena.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Additional Important Safety Information   

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