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Sex after menopause
shouldn't have to hurt

It is a common medical condition that can be treated.

Osphena® (ospemifene) is the only oral, non-estrogen treatment FDA-approved for moderate to severe painful sex after menopause.

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Watch a video about Patti, an actual Osphena user, discussing her treatment journey and experience using Osphena.

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How does Osphena work?

With continued use*, Osphena can improve specific vaginal tissue that’s causing the pain.

  • Osphena works at the tissue level in the vagina and may require some time to take effect. Clinical studies show that with continued use, in as early as 12 weeks:
  • Most women reported relief from the pain of moderate to severe painful sex due to menopause
  • One pill, once daily—to get the best results with Osphena, take it once a day, orally, with food

*You and your healthcare provider should talk regularly (every 3 to 6 months) about the dose you are taking and whether or not you still need treatment with Osphena.

With Osphena, you may experience relief in as early as 12 weeks.

Individual results may vary.

Lubricants can only provide temporary relief

Lubricants

Sure, over-the-counter lubricants can give you short-term relief. But, with continued use, Osphena treats moderate to severe painful sex. In as little as 12 weeks, it improves specific vaginal tissue that changes due to menopause.

Osphena made a difference for me.

Osphena is the only oral, non-hormonal treatment for moderate to severe painful sex after menopause

Consider your treatment options

Non-Hormonal vs. Hormonal

This table is not intended for comparative purposes.

Non-Hormonal vs. Hormonal

This table is not intended for comparative purposes.

Want to speak to a healthcare professional about Osphena?

Call 1-855-OSPHENA (1-855-677-4362) Monday to Friday, 8:00am to 8:00pm

If you’re looking for additional information about Osphena, click below to view our Frequently Asked Questions.

Get Answers to Questions About Osphena

Osphena offers a great savings program that may make this treatment an option you can afford.

Get Savings on Your Osphena Prescription

See Full Terms, Conditions, Eligibility Rules & Patient Information, including Maximum Benefit, on the Savings Card.

Indication and Important Safety Information

What is Osphena® (ospemifene) tablets?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse, a symptom of changes in and around your vagina, due to menopause.

Important Safety Information for Osphena

Most Important Information you should know about Osphena

Osphena works like estrogen in the lining of the uterus, but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause; so tell them right away if this happens while you are using Osphena.

Osphena may increase your chance of getting strokes and blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you get changes in vision or speech, sudden new severe headaches, and severe pains in your chest or legs with or without shortness of breath, weakness and fatigue. Osphena should not be used if you have unusual vaginal bleeding; have or have had certain types of cancers (including cancer of the breast or uterus); have or had blood clots; had a stroke or heart attack; have severe liver problems; are allergic to Osphena or any of its ingredients; or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

Possible side effects of Osphena

Serious but less common side effects can include stroke, blood clots, and cancer of the lining of the uterus.

Common side effects can include hot flashes, vaginal discharge, muscle spasms and increased sweating.

Tell your healthcare provider about all of the medicines and supplements you take as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

Please read accompanying Patient Information for Osphena® (ospemifene) tablets, including Boxed WARNING in the U.S. Full Prescribing Information.

Important Safety Information and Indication

Most Important Information you should know about Osphena®

Osphena works like estrogen in the lining of the uterus, but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause; so tell them right away if this happens while you are using Osphena.

Osphena may increase your chance of getting strokes and blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you get changes in vision or speech, sudden new severe headaches, and severe pains in your chest or legs with or without shortness of breath, weakness and fatigue. Osphena should not be used if you have unusual vaginal bleeding; have or have had certain types of cancers (including cancer of the breast or uterus); have or had blood clots; had a stroke or heart attack; have severe liver problems; are allergic to Osphena or any of its ingredients; or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

Possible side effects of Osphena

Serious but less common side effects can include stroke, blood clots, and cancer of the lining of the uterus.

Common side effects can include hot flashes, vaginal discharge, muscle spasms and increased sweating.

Tell your healthcare provider about all of the medicines and supplements you take as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

What is Osphena® (ospemifene) tablets?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse, a symptom of changes in and around your vagina, due to menopause.

Please read accompanying Patient Information for Osphena® (ospemifene) tablets, including Boxed WARNING in the U.S. Full Prescribing Information.

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