Vaginal changes due to menopause
|Before menopause, estrogen helps maintain||After menopause, falling estrogen levels mean|
|Thickness and elasticity (stretchiness) of your vaginal tissue||Your vagina becomes shorter and narrower and your vaginal lining becomes thinner and less elastic|
|Sufficient blood vessels in your vaginal walls||Less blood flows to your vagina|
|Good lubrication during daily and sexual activities||Your vagina produces fewer secretions, resulting in less lubrication during sexual stimulation|
Although Osphena® is taken by mouth, it works in your vagina to increase the number of one type of cell (superficial cells), decrease the number of another type of cell (parabasal cells) and helps reduce vaginal pH to help relieve both moderate to severe vaginal dryness and moderate to severe painful sex due to menopause.
How effective is Osphena®?
After just 12 weeks of treatment, studies showed Osphena® helped increase the proportion of superﬁcial cells (cells that you need more of), helped decrease the proportion of parabasal cells (cells that you need less of), and helped lower vaginal pH, to improve vaginal health.
How safe is Osphena®?
Osphena® is not an estrogen. It is a non-hormonal treatment that specifically targets vaginal tissue.
Osphena®'s safety has been confirmed in multiple clinical trials. It has been prescribed over 1 million times since its launch in 2013 and is recommended as Level A treatment for dyspareunia (meaning that it is supported by the highest level of clinical evidence) by the American College of Obstetricians and Gynecologists (ACOG) and the North American Menopause Society (NAMS).
How to take Osphena®?
Take one 60 mg Osphena® tablet once daily, by mouth, with food.
If you miss a dose, wait until your next regularly scheduled pill. Do not take two pills in the same day.
Osphena® should be taken for the shortest duration consistent with treatment goals and risks for the individual woman.