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Menopause symptoms rubbing you the wrong way? Ask your healthcare provider for Osphena®.

Osphena® is the first and only once-daily, oral, non-hormonal treatment for moderate to severe vaginal dryness and/or moderate to severe painful intercourse, symptoms of changes in and around your vagina due to menopause.

How Osphena Helps

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Retail Pharmacy

Osphena® Savings Card

If you have commercial insurance

Pay as little as

$35*for 30 tablets

Questions? Call (347) 657-9766

Apollo Care Processing Information:

Bin: 637765

Group ID: 99992002

RxPCN: CRX

#ID: 46611500801

If your insurance does not cover Osphena® or you do not have insurance:

GoodRx logo GoodRx Savings Offer

Pay as little as:

  • $2.50*

    /tablet for > 60 tablets**

  • $99*

    for 30 tablets

  • $225*

    for 90 tablets

GoodRx Processing Information

Bin: 610020

Group ID: 99995428

RxPCN: PDM

#ID: EROXOSPHENA

GoodRx is NOT insurance. Cancel anytime. By continuing, you agree to the GoodRx Terms of Use and Privacy Policy available at goodrx.com/terms. ©2025 GoodRx, Inc., 2701 Olympic Blvd., Santa Monica, CA 90404.

*See terms and conditions

**Price per tablet may vary for quantities less than 60 tablets

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IMPORTANT SAFETY INFORMATION INCLUDING BOXED WARNING AND INDICATION

Indication: What is Osphena?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse and/or moderate to severe vaginal dryness, both symptoms of changes in your vagina, due to menopause.

Most Important Information you should know about Osphena

WARNING: ENDOMETRIAL CANCER and CARDIOVASCULAR DISORDERS

Osphena works like estrogen in the lining of the uterus (endometrium), but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell him or her right away if this happens while you are using Osphena.

Osphena may increase your chances of having a stroke or blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you have unusual vaginal bleeding, changes in vision or speech, sudden new severe headaches, and pains in your chest or legs with or without shortness of breath, weakness and fatigue.

Who should not take OSPHENA?

Osphena should not be used if you have unusual vaginal bleeding, have or have had certain types of cancers, have or have had blood clots, had a stroke or heart attack, have severe liver problems, are allergic to Osphena or any of its ingredients, or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

POSSIBLE SIDE EFFECTS

Serious but less common side effects can include:

  • stroke
  • blood clots
  • cancer of the lining of the uterus

Less serious, but common side effects include:

  • hot flushes or flashes
  • vaginal discharge
  • muscle spasms
  • headache
  • excessive sweating (hyperhidrosis)
  • heavy vaginal bleeding (vaginal hemorrhage)
  • night sweats

Tell your healthcare provider about all of the medicines and supplements you take, as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read Patient Information for Osphena (ospemifene) tablets, including Boxed Warning and the Full Prescribing Information.

INDICATION AND IMPORTANT SAFETY INFORMATION

INDICATION: WHAT IS OSPHENA?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse and/or moderate to severe vaginal dryness, both symptoms of changes in your vagina, due to menopause.

IMPORTANT SAFETY INFORMATION

WARNING: ENDOMETRIAL CANCER and CARDIOVASCULAR DISORDERS

See full Prescribing Information for complete Boxed Warning.

Osphena works like estrogen in the lining of the uterus (endometrium), but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell him or her right away if this happens while you are using Osphena.

INDICATION AND IMPORTANT SAFETY INFORMATION

INDICATION: WHAT IS OSPHENA?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse and/or moderate to severe vaginal dryness, both symptoms of changes in your vagina, due to menopause.

IMPORTANT SAFETY INFORMATION

WARNING: ENDOMETRIAL CANCER and CARDIOVASCULAR DISORDERS

See full Prescribing Information for complete Boxed Warning.

Osphena works like estrogen in the lining of the uterus (endometrium), but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause, so tell him or her right away if this happens while you are using Osphena.

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