After menopause, Estrogen levels decline, which causes the vagina to change and -- sex can become painful.
But treatment for moderate to severe painful sex after menopause is available.

Menopause causes vaginal changes.

Menopause — for women, it’s a fact of life. As we age, a decline in estrogen changes the vaginal tissues, which can lead to painful sex.

As our estrogen levels start to naturally decline with age, sex may become painful.


The medical term for painful sex is dyspareunia (pronounced dis-puh-roo-nee-uh). Painful sex is one of the most bothersome symptoms of vulvar and vaginal atrophy (VVA).

Fact: It's very common.

Wondering if you are the only one experiencing painful sex after menopause? The answer is NO — not by a longshot. It's not just you — it’s very natural and normal. You are one of the many women experiencing it.

  •   It is estimated as many as 1 in 3 postmenopausal women experience painful sex.

We spend about one-third of our lives after menopause. Sure, we might be a bit older now, but that doesn’t mean we’re not having sex anymore. Sex is healthy. Unlike hot flashes, painful sex will not go away on its own. Left untreated, it can get worse. So, isn’t it time to speak up and talk to your healthcare provider
about it?

Osphena® works at the cellular level.

Osphena is the only FDA-approved, non-estrogen, oral treatment for moderate to severe painful intercourse due to menopause. Osphena works at the cellular level by improving specific vaginal tissue, which can significantly relieve moderate to severe painful sex due to menopause. Lubricants can offer temporary relief of painful sex, but they can’t improve the tissue.

Sex after menopause shouldn't have to hurt.

Osphena is proven to
improve specific
vaginal tissue.
Lubricants can't do that.

Take charge and start the conversation with your doctor. Ask about Osphena®.

Sex after menopause is still important. If you're experiencing moderate to severe painful sex, do something about it. You deserve to be heard.

Not sure what to say? Download a doctor discussion guide to help you prepare for an effective talk with your doctor about treatment options.

Download My Guide

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Indication and Important Safety Information

Important Safety Information and Indication

What is Osphena® (ospemifene) tablets?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse, a symptom of changes in and around your vagina, due to menopause.

Important Safety Information for Osphena

Most Important Information you should know about Osphena®

Osphena works like estrogen in the lining of the uterus, but can work differently in other parts of the body. Taking estrogen alone or Osphena may increase your chance for getting cancer of the lining of the uterus. Vaginal bleeding after menopause may be a warning sign of cancer of the lining of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause; so tell them right away if this happens while you are using Osphena.

Osphena may increase your chance of getting strokes and blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with Osphena.

Call your healthcare provider right away if you get changes in vision or speech, sudden new severe headaches, and severe pains in your chest or legs with or without shortness of breath, weakness and fatigue. Osphena should not be used if you have unusual vaginal bleeding; have or have had certain types of cancers (including cancer of the breast or uterus); have or had blood clots; had a stroke or heart attack; have severe liver problems; are allergic to Osphena or any of its ingredients; or think you may be pregnant. Tell your healthcare provider if you are going to have surgery or will be on bed rest.

Possible side effects of Osphena

Serious but less common side effects can include stroke, blood clots, and cancer of the lining of the uterus.

Common side effects can include hot flashes, vaginal discharge, muscle spasms and increased sweating.

Tell your healthcare provider about all of the medicines and supplements you take as some medicines may affect how Osphena works. Osphena may also affect how other medicines work.

What is Osphena® (ospemifene) tablets?

Osphena is a prescription oral pill that treats moderate to severe painful intercourse, a symptom of changes in and around your vagina, due to menopause.

Please read accompanying Patient Information for Osphena® (ospemifene) tablets, including Boxed WARNING in the U.S. Full Prescribing Information.